BDBM50084287 (S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::CHEMBL45040

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C#N)C(O)=O

InChI Key InChIKey=AGRDSOUIPBKOKQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50084287   

TargetStromelysin-1(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084287((S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084287((S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl...)
Affinity DataIC50: 33nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084287((S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl...)
Affinity DataIC50: 37nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084287((S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084287((S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl...)
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50084287((S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl...)
Affinity DataIC50: 5.89E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50084287((S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl...)
Affinity DataIC50: 5.90E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed