BDBM50084295 2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::CHEMBL42938

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C#N)C(O)=O

InChI Key InChIKey=AGRDSOUIPBKOKQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084295   

TargetStromelysin-1(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084295(2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-but...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084295(2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-but...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084295(2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-but...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084295(2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-but...)
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084295(2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-but...)
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084295(2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-but...)
Affinity DataIC50: 1.90E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed