BDBM50084332 (2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piperidin-3-ylmethyl]-amine::CHEMBL67203

SMILES C(CN1CCCC(CNCCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1

InChI Key InChIKey=IQRFNUMAKGJEQR-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084332   

TargetSodium-dependent dopamine transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084332((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataKi:  18nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084332((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataKi:  23nMAssay Description:Binding affinity at the norepinephrine transporter was measured using [125I]RTI-55 as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084332((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 97nMAssay Description:Inhibition of [3H]NE reuptake by human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084332((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [3H]dopamine reuptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084332((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataKi:  210nMAssay Description:Binding affinity for serotonin transporter using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084332((2-Benzhydryloxy-ethyl)-[1-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 820nMAssay Description:Inhibition of [3H]5-HT reuptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed