BDBM50084495 CHEMBL328283::{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine (2HCL .1/2H2O)

SMILES COc1ccc2CCCC(NCCN3CCN(CC3)c3ccc(Cl)cc3)c2c1

InChI Key InChIKey=MFLTUPXICJHQFA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084495   

TargetD(4) dopamine receptor(Human)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084495({2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-(7-...)
Affinity DataKi:  46nMAssay Description:In vitro binding affinity at human Dopamine receptor D4.4 by [3H]YM-09151-2 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084495({2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-(7-...)
Affinity DataKi:  262nMAssay Description:In vitro binding affinity at human Dopamine receptor D2 (long) by [3H]spiroperidol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084495({2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-(7-...)
Affinity DataKi: >850nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine receptor 1A receptor in rat hippocampal membranes by [3H]8-OH-DPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed