BDBM50084724 6-Methyl-4,8a-di-p-tolyl-hexahydro-[1,3]dioxino[5,4-c]pyridin-2-one::CHEMBL120269

SMILES CN1CCC2(OC(=O)OC(C2C1)c1ccc(C)cc1)c1ccc(C)cc1

InChI Key InChIKey=BGZGKVAVORWNIY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084724   

TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084724(6-Methyl-4,8a-di-p-tolyl-hexahydro-[1,3]dioxino[5,...)
Affinity DataKi:  8.19E+3nMAssay Description:Binding Affinity to cocaine site of dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]mazindol. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084724(6-Methyl-4,8a-di-p-tolyl-hexahydro-[1,3]dioxino[5,...)
Affinity DataKi:  9.48E+3nMAssay Description:Inhibition of [3H]DA Uptake at dopamine transporter in rat cortex was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed