BDBM50084731 4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 1-(cyclopropylmethyl-propyl-amide) 3-hydroxyamide::CHEMBL125672

SMILES CCCN(CC1CC1)C(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OC)cc1

InChI Key InChIKey=PNVLBMRGQMDPBJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084731   

TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084731(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50: 493nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084731(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50: 2.09E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084731(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084731(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084731(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50: 65nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed