BDBM50084740 4-(Isoxazole-5-carbonyl)-1-(4-methoxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL436580

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1ccno1

InChI Key InChIKey=QKBHNYUMIYQZNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084740   

TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084740(4-(Isoxazole-5-carbonyl)-1-(4-methoxy-benzenesulfo...)
Affinity DataIC50: 62nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50084740(4-(Isoxazole-5-carbonyl)-1-(4-methoxy-benzenesulfo...)
Affinity DataIC50: 147nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50084740(4-(Isoxazole-5-carbonyl)-1-(4-methoxy-benzenesulfo...)
Affinity DataIC50: 147nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed