BDBM500848 4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- [(2S)-2- (imidazol-1- ylmethyl)mor- pholin-4-yl]-2- pyridyl]amino] isoindolin-1-one::US11021481, Compound I-512::US11078201, Compound I-512::US11548890, Compound I-512

SMILES Fc1ccn2c(cnc2c1)-c1ccc(Nc2ccc(cn2)N2CCO[C@H](Cn3ccnc3)C2)c2C(=O)NCc12

InChI Key InChIKey=UBYSZRRKDHAOFP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500848   

LigandPNGBDBM500848(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500848(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500848(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500848(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500848(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent