BDBM50084985 CHEMBL3427404

SMILES CN(c1ccc(\C=C\C(O)=O)cc1)c1c(-c2ccc(F)cc2C)c(=O)oc2cc(O)ccc12

InChI Key InChIKey=MXKFWFABWNUKCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084985   

TargetEstrogen receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084985(CHEMBL3427404)
Affinity DataIC50: 9.90nMAssay Description:Binding affinity to ER alpha (unknown origin) by LanthaScreen TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084985(CHEMBL3427404)
Affinity DataIC50: 60nMAssay Description:Suppression of ER alpha in human MCF7 cells after 24 hrs by immunostaining analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed