BDBM50084989 (S)-2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-7-thiophen-3-yl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid::CHEMBL418080

SMILES Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2cc(ccc2C[C@H]1C(O)=O)-c1ccsc1

InChI Key InChIKey=XJUFWAWETNPMLY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084989   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50084989((S)-2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...)
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for binding affinity towards Opioid receptor delta 1 by displacing 125 I-deltorphin IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50084989((S)-2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...)
Affinity DataIC50: 2.73E+3nMAssay Description:Compound was evaluated for binding affinity towards Opioid receptor kappa 1 by displacing 125 I-DPDYNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50084989((S)-2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...)
Affinity DataIC50: 142nMAssay Description:Compound was evaluated for binding affinity towards Opioid receptor mu 1 by displacing 125 I-FK-33824More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed