BDBM50084997 4-(3,4-Difluoro-phenyl)-2,5-dioxo-1,2,5,7-tetrahydro-4H-furo[3,4-d]pyrimidine-3-carboxylic acid [3-(4-cyano-4-phenyl-piperidin-1-yl)-propyl]-amide::CHEMBL298579

SMILES Fc1ccc(cc1F)C1N(C(=O)NCCCN2CCC(CC2)(C#N)c2ccccc2)C(=O)NC2=C1C(=O)OC2

InChI Key InChIKey=YXGDGGYNHGGLOW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084997   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50084997(4-(3,4-Difluoro-phenyl)-2,5-dioxo-1,2,5,7-tetrahyd...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50084997(4-(3,4-Difluoro-phenyl)-2,5-dioxo-1,2,5,7-tetrahyd...)
Affinity DataKi:  970nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50084997(4-(3,4-Difluoro-phenyl)-2,5-dioxo-1,2,5,7-tetrahyd...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]- prazosin from human recombinant Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed