BDBM50085448 (S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid 4-carbamimidoyl-benzylamide::CHEMBL312145::D-Phe-Pro-p-amindinobenzylamine

SMILES N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=VZFTWWJAUZOJDH-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085448   

TargetThyroid hormone receptor beta(Human)
Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50085448(D-Phe-Pro-p-amindinobenzylamine | (S)-1-((R)-2-Ami...)
Affinity DataKd:  0.550nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50085448(D-Phe-Pro-p-amindinobenzylamine | (S)-1-((R)-2-Ami...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50085448(D-Phe-Pro-p-amindinobenzylamine | (S)-1-((R)-2-Ami...)
Affinity DataKi:  1.5nMAssay Description:Concentration required for 50 percent inhibition of ProthrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed