BDBM50085451 (3S,6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-indolizine-3-carboxylic acid 4-carbamimidoyl-benzylamide::CHEMBL79705

SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CC[C@H]3CC[C@@](O)(Cc4ccccc4)C(=O)N23)cc1

InChI Key InChIKey=PVTGBPNXHBYAJX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085451   

TargetProthrombin(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50085451((3S,6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-ind...)
Affinity DataKi:  9nMAssay Description:The compound was evaluated for binding affinity against ProthrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50085451((3S,6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-ind...)
Affinity DataIC50: 20nMAssay Description:Concentration required for 50 percent inhibition of ProthrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed