BDBM50085455 CHEMBL89760::{(S)-7-[(R)-2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]-8-oxo-7,8-dihydro-6H-5-oxa-9-aza-benzocyclohepten-9-yl}-acetic acid

SMILES ON(C[C@@H](Cc1ccccc1)C(=O)N[C@H]1COc2ccccc2N(CC(O)=O)C1=O)C=O

InChI Key InChIKey=QSQZXLYXKLWOQU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085455   

TargetNeprilysin(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085455({(S)-7-[(R)-2-Benzyl-3-(formyl-hydroxy-amino)-prop...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085455({(S)-7-[(R)-2-Benzyl-3-(formyl-hydroxy-amino)-prop...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085455({(S)-7-[(R)-2-Benzyl-3-(formyl-hydroxy-amino)-prop...)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085455({(S)-7-[(R)-2-Benzyl-3-(formyl-hydroxy-amino)-prop...)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed