BDBM50085601 CHEMBL3427723

SMILES COCCOc1ccc(Cl)c(c1)-c1nnc2c(C)nc3ccncc3n12

InChI Key InChIKey=GKLYIDCVESZPKM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085601   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50085601(CHEMBL3427723)Copy SMILESCopy InChI

Affinity DataIC50: 95nMAssay Description:Inhibition of 6-His-tagged human recombinant PDE2A expressed in Sf9 cells using [3H]cGMP incubated for 40 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/5/2016
Entry Details Article
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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50085601(CHEMBL3427723)Copy SMILESCopy InChI

Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of 6-His-tagged rat recombinant PDE10A expressed in Sf9 cells using [3H]cAMP incubated for 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/5/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL