BDBM50085672 (2R,3R,4S,5R)-2-(6-Amino-2-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol::CHEMBL128176::N6-Cyclopentylado (CPA)

SMILES Nc1nc(NC2CCCC2)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=QRDVRBCDBYRKMD-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085672   

TargetPhosphoglycerate kinase 1(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50085672(CHEMBL128176 | N6-Cyclopentylado (CPA) | (2R,3R,4S...)
Affinity DataIC50: 1.50E+6nMAssay Description:evaluated for the inhibition of Trypanosoma brucei Phosphoglycerate kinase (PGK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50085672(CHEMBL128176 | N6-Cyclopentylado (CPA) | (2R,3R,4S...)
Affinity DataKi:  0.589nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085672(CHEMBL128176 | N6-Cyclopentylado (CPA) | (2R,3R,4S...)
Affinity DataKi:  5.10nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50085672(CHEMBL128176 | N6-Cyclopentylado (CPA) | (2R,3R,4S...)
Affinity DataKi:  462nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetAdenosine receptor A1(Guinea pig)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50085672(CHEMBL128176 | N6-Cyclopentylado (CPA) | (2R,3R,4S...)
Affinity DataKi:  549nMAssay Description:Ex vivo inhibition of guinea pig ileum twitch via Adenosine A1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed