BDBM50085867 2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)propylamino)-1,4-dioxobutan-2-ylcarbamoyl)cyclohexylamino)-2-(carboxyformamido)-3-oxopropyl)phenyl)malonic acid::2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::CHEMBL303150

SMILES NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12

InChI Key InChIKey=ZOJQPGFTWKKVQO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085867   

TargetGrowth factor receptor-bound protein 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)
Affinity DataIC50: 22nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)
Affinity DataIC50: 22.1nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity in ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Grb2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed