BDBM50086248 CHEMBL3425756

SMILES CCNc1nc(Cc2ccccc2)cc2CCNCCc12

InChI Key InChIKey=ONTAWQDMHIOMGP-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086248   

Target5-hydroxytryptamine receptor 2C(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086248(CHEMBL3425756)
Affinity DataKi:  3nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086248(CHEMBL3425756)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 30 to 40 mins by GTPgammaS recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086248(CHEMBL3425756)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human recombinant 5-HT2B receptor expressed in CHOK1 cells assessed as induction of Ca2+ mobilization after 1 hr by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed