BDBM50086522 (8,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-pyrido[3,2-g]quinolin-2-yl)-(4-methoxy-benzyl)-amine::CHEMBL134117

SMILES COc1ccc(CNc2cc(c3cc4CCC(C)(C)Nc4cc3n2)C(F)(F)F)cc1

InChI Key InChIKey=XTZSOANPEICZQS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086522   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086522((8,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for human androgen receptor transfected into mammalian COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086522((8,8-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro...)
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibitory concentration against human androgen receptor (AR) dependent transcriptional activity in co-transfected mammalian CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed