BDBM50086630 (1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetyl}-piperidin-2-yl)-acetic acid; TFA::CHEMBL141289

SMILES NC(=N)c1ccc(cc1)C1=NOC(CC(=O)N2CCCCC2CC(O)=O)C1

InChI Key InChIKey=FCGAIJHNBXQCGH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50086630   

TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 2nMAssay Description:Inhibition of GPIIb/IIIa binding in activated human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 2nMAssay Description:Inhibition of GPIIb/IIIa binding in activated human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 64nMAssay Description:Inhibition of Platelet glycoprotein IIb/Platelet glycoprotein IIIa binding in unactivated human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 64nMAssay Description:Inhibition of Platelet glycoprotein IIb/Platelet glycoprotein IIIa binding in unactivated human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 110nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (hPRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 110nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (hPRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 280nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (hPRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (hPRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of GPIIb/IIIa binding in activated human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of Platelet glycoprotein IIb/Platelet glycoprotein IIIa binding in unactivated human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086630((1-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isox...)
Affinity DataIC50: 9.80E+6nMAssay Description:Inhibition of GPIIb/IIIa binding in activated human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed