BDBM50086861 3-Methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-ylmethyl)-benzamide::CHEMBL356304

SMILES CSc1cccc(c1)C(=O)NC[C@@H]1CCCN1CCc1ccccc1

InChI Key InChIKey=LABFIALYPYPGFW-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50086861   

Target5-hydroxytryptamine receptor 1A(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50086861(3-Methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-y...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50086861(3-Methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-y...)
Affinity DataKi:  4.30nMAssay Description:Inhibitory concentration against binding of 5-hydroxytryptamine 1A receptor from striata of male Wistar rats by displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50086861(3-Methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-y...)
Affinity DataKi:  160nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50086861(3-Methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against binding of Dopamine receptor D2 by displacement of [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed