BDBM50086875 6-[5-(4-Methyl-piperazine-1-sulfonyl)-2-propoxy-phenyl]-3,7-dihydro-imidazo[4,5-g]quinazolin-8-one::CHEMBL22906

SMILES CCCOc1ccc(cc1-c1nc2cc3[nH]cnc3cc2c(=O)[nH]1)S(=O)(=O)N1CCN(C)CC1

InChI Key InChIKey=OJQQFXIVAUZCJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086875   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086875(6-[5-(4-Methyl-piperazine-1-sulfonyl)-2-propoxy-ph...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed