BDBM50087009 8-(8-Chloro-1,2,3,4-tetrahydro-naphthalen-2-yl)-3-methoxymethyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL283432

SMILES COCN1CN(c2ccccc2)C2(CCN(CC2)C2CCc3cccc(Cl)c3C2)C1=O

InChI Key InChIKey=ZEJXBBLSIGQZQJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087009   

TargetMu-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087009(8-(8-Chloro-1,2,3,4-tetrahydro-naphthalen-2-yl)-3-...)
Affinity DataKi:  7.5nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087009(8-(8-Chloro-1,2,3,4-tetrahydro-naphthalen-2-yl)-3-...)
Affinity DataKi:  8.5nMAssay Description:Competitive binding affinity against transfected HEK293 cells expressing Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087009(8-(8-Chloro-1,2,3,4-tetrahydro-naphthalen-2-yl)-3-...)
Affinity DataKi:  18nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087009(8-(8-Chloro-1,2,3,4-tetrahydro-naphthalen-2-yl)-3-...)
Affinity DataKi:  240nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed