BDBM50087158 5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-pentanoic acid (3-dibutylamino-propyl)-amide::CHEMBL160637

SMILES CCCCN(CCCC)CCCNC(=O)CCC=Cc1c(C)c(O)c2cccc(O)c2c1O

InChI Key InChIKey=MKOSAXKPEBSBNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087158   

TargetTrypanothione reductase(Trypanosoma cruzi)
Université

Curated by ChEMBL
LigandPNGBDBM50087158(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)
Affinity DataIC50: 300nMAssay Description:Concentration required for inhibition of Trypanothione reductase (TcTR) from Trypanosoma cruzi in the presence of 50 uM TS2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Univ Paris Sud

Curated by ChEMBL
LigandPNGBDBM50087158(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed