BDBM50087638 (R)-5-Guanidino-2-phenylmethanesulfonylamino-pentanoic acid [((S)-1-carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-amide; TFA::CHEMBL423823

SMILES NC(=N)NCCC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)N[C@H]1CCCN(C1O)C(N)=N

InChI Key InChIKey=HSCSARKJCAZJSX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087638   

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087638((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087638((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087638((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 1.19E+3nMAssay Description:In vitro inhibition of human plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087638((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed