BDBM50087639 (R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-3-(1-carbamimidoyl-piperidin-4-yl)-2-(2-tetrazol-1-yl-phenylmethanesulfonylamino)-propionamide; TFA::CHEMBL164419

SMILES NC(=N)N1CCC(C[C@@H](NS(=O)(=O)Cc2ccccc2-n2cnnn2)C(=O)NCC(=O)N[C@H]2CCCN(C2O)C(N)=N)CC1

InChI Key InChIKey=DPHOZKUFKPCNOS-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50087639   

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087639((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 2.60nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087639((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataKi:  23nMAssay Description:Concentration required for classical fast inhibition of cleavage of the chromogenic substrate by human enzyme Coagulation factor X in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087639((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 537nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087639((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 872nMAssay Description:In vitro inhibition of human plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087639((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed