BDBM50087640 2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-2-(1-carbamimidoyl-piperidin-3-yl)-ethylsulfamoyl]-methyl}-benzoic acid methyl ester; TFA::CHEMBL352119

SMILES COC(=O)c1ccccc1CS(=O)(=O)N[C@H](CC1CCCN(C1)C(N)=N)C(=O)NCC(=O)N[C@H]1CCCN(C1O)C(N)=N

InChI Key InChIKey=CWBPPDBIZLIFDM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50087640   

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: 1.37nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: 1.95E+3nMAssay Description:In vitro inhibition of human plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: 1.95E+3nMAssay Description:In vitro inhibition of human plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed