BDBM50087659 4N,4N-dimethyl-1-{4-[4-(4-dimethylamino-1-pyridiniumylmethyl)phenethyl]benzyl}-4-pyridiniumamine dibromide::CHEMBL164903

SMILES C[N+](C)=c1ccn(Cc2ccc(CCc3ccc(Cn4ccc(cc4)=[N+](C)C)cc3)cc2)cc1

InChI Key InChIKey=MWFDXNKLQQGWGN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087659   

TargetAcetylcholinesterase(Bovine)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50087659(4N,4N-dimethyl-1-{4-[4-(4-dimethylamino-1-pyridini...)
Affinity DataIC50: 628nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50087659(4N,4N-dimethyl-1-{4-[4-(4-dimethylamino-1-pyridini...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholine kinase alpha(Human)
Granada

Curated by ChEMBL
LigandPNGBDBM50087659(4N,4N-dimethyl-1-{4-[4-(4-dimethylamino-1-pyridini...)
Affinity DataIC50: 1.70E+4nMAssay Description:Compound was tested ex vivo for inhibition against purified choline kinase obtained from yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed