BDBM50087663 1,2-di[4-(4-tetrahydro-1H-1-pyrrolyl-1-pyridiniumylmethyl)phenyl]ethane dibromide::CHEMBL350410

SMILES C(Cc1ccc(Cn2ccc(cc2)=[N+]2CCCC2)cc1)c1ccc(Cn2ccc(cc2)=[N+]2CCCC2)cc1

InChI Key InChIKey=WXLINZANXGBOSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087663   

TargetAcetylcholinesterase(Bovine)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50087663(1,2-di[4-(4-tetrahydro-1H-1-pyrrolyl-1-pyridiniumy...)
Affinity DataIC50: 385nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50087663(1,2-di[4-(4-tetrahydro-1H-1-pyrrolyl-1-pyridiniumy...)
Affinity DataIC50: 735nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholine kinase alpha(Human)
Granada

Curated by ChEMBL
LigandPNGBDBM50087663(1,2-di[4-(4-tetrahydro-1H-1-pyrrolyl-1-pyridiniumy...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound was tested ex vivo for inhibition against purified choline kinase obtained from yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed