BDBM50087820 CHEMBL3426797

SMILES CC1(C)CC(=O)C2=C(C1)OC1=C(C2c2ccc(OCc3ccccc3Br)cc2)C(=O)CC(C)(C)C1

InChI Key InChIKey=BBCHHZHONQIODT-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087820   

TargetMu-type opioid receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087820(CHEMBL3426797)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mu opioid receptor-1 expressed in CHO cells assessed as potentiation of endomorphin 1-induced response after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087820(CHEMBL3426797)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of human delta opioid receptor-1 expressed in CHO cells assessed as potentiation of leu-enkephalin-induced response af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087820(CHEMBL3426797)
Affinity DataEC50:  1.91E+8nMAssay Description:Inhibition of human DOR expressed in CHO cells assessed as reduction in Leu-enkephalin induced ERK1/2 phosphorylation level by measuring Leu-enkephal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087820(CHEMBL3426797)
Affinity DataEC50:  1.41E+8nMAssay Description:Inhibition of human DOR expressed in CHO cells assessed as reduction in Leu-enkephalin induced cAMP level by measuring Leu-enkephalin pEC50 measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed