BDBM50087856 CHEMBL3426913

SMILES CCCCC(Oc1cc(O)c(cc1C#Cc1ccccc1OC(F)(F)F)C(O)=O)C(=O)NC1CCCCC1

InChI Key InChIKey=DPPSTFALTNIFPF-UHFFFAOYSA-N

Data  1 KI  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50087856   

TargetDual specificity protein phosphatase 3(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 6.00E+3nMpH: 7.0Assay Description:Inhibition of VHR (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetUbiquitin-like domain-containing CTD phosphatase 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 500nMpH: 6.0Assay Description:Inhibition of His6-tagged UBLCP1 (unknown origin) expressed in Escherichia coli BL21 cells using pNPP as substrate at pH 6 at 25 degC by spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 7.20E+3nMpH: 7.0Assay Description:Inhibition of CDC14A (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 3(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 1.39E+4nMpH: 7.0Assay Description:Inhibition of PTPH1 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 14(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 8.30E+3nMpH: 7.0Assay Description:Inhibition of PEZ (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of LAR (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of LMWPTP (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 1.28E+4nMpH: 7.0Assay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of STEP (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 1.01E+4nMpH: 7.0Assay Description:Inhibition of TC-PTP (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetLaforin(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 1.03E+4nMpH: 7.0Assay Description:Inhibition of Laforin (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.70E+3nMpH: 7.0Assay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 23(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 1.14E+4nMpH: 7.0Assay Description:Inhibition of VHZ (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 8.00E+3nMpH: 7.0Assay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.40E+3nMpH: 7.0Assay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 8.70E+3nMpH: 7.0Assay Description:Inhibition of HePTP (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of PTPepsilon (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase gamma(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of PTPgamma (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of PP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of SCP1 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetUbiquitin-like domain-containing CTD phosphatase 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataKi:  1.00E+3nMAssay Description:Competitive inhibition of His6-tagged UBLCP1 (unknown origin) expressed in Escherichia coli BL21 cells by Lineweaver-Burk plot analysis in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed