BDBM50088508 CHEMBL3526978

SMILES COc1cc(ccc1C#CC1CC1)C(=O)NS(=O)(=O)c1ccccc1S(N)(=O)=O

InChI Key InChIKey=KFWMCPHFJZDJRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088508   

TargetProstaglandin E synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50088508(CHEMBL3526978)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human mPGES-1 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50088508(CHEMBL3526978)
Affinity DataIC50: 340nMAssay Description:Inhibition of human mPGES-1 expressed in Sf9 insect cells assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed