BDBM50088854 CHEMBL3577633

SMILES COc1cccc(c1)N1C(=O)\C(=C\c2ccc(OCC(=O)Nc3ccccc3Cl)cc2)N=C1c1ccccc1

InChI Key InChIKey=BJNJWWZVYQINAM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088854   

TargetMitogen-activated protein kinase 3(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50088854(CHEMBL3577633)
Affinity DataIC50: 87nMAssay Description:Inhibition of ERK1 (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50088854(CHEMBL3577633)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of p38alpha MAP kinase (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50088854(CHEMBL3577633)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of ERK2 (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed