BDBM50089005 (S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amino]-3-[4-(2,6-dichloro-benzyloxy)-phenyl]-propionic acid::2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amino]-3-[4-(2,6-dichloro-benzyloxy)-phenyl]-propionic acid::CHEMBL351547

SMILES CC(=O)N1CSC[C@@H]1C(=O)N[C@@H](Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)C(O)=O

InChI Key InChIKey=YBKFCWABWAQJTN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50089005   

TargetIntegrin alpha-4/beta-7(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of alpha4-beta7 integrin mediated cell adhesionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of alpha5-beta1 integrin mediated cell adhesionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 4.00E+5nMAssay Description:The antagonist activity was evaluated by alphaIlb-beta3 cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of alphaL-beta2 mediated cell adhesionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 34nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 5nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of alphaV-beta3 mediated cell adhesionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech Chiroscience

Curated by ChEMBL
LigandPNGBDBM50089005(2-[((4S,5S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50: 410nMAssay Description:In vitro inhibition of binding of integrin alpha4-beta1 to immobilized VCAM-1 expressed on endothelial cell surface.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed