BDBM50089109 CHEMBL278780::[2-{4-[3-(2-Chloro-phenyl)-ureido]-butylcarbamoyl}-1-(1H-indol-3-ylmethyl)-1-phenethylcarbamoyl-ethyl]-carbamic acid adamantan-2-yl ester

SMILES Clc1ccccc1NC(=O)NCCCCNC(=O)CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCCc1ccccc1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089109   

TargetGastrin/cholecystokinin type B receptor(Mouse)
Ccipe-Faculte De Pharmacie

Curated by ChEMBL
LigandPNGBDBM50089109([2-{4-[3-(2-Chloro-phenyl)-ureido]-butylcarbamoyl}...)
Affinity DataIC50: 3.60E+3nMAssay Description:Binding affinity towards Cholecystokinin type B receptor in mouse cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Ccipe-Faculte De Pharmacie

Curated by ChEMBL
LigandPNGBDBM50089109([2-{4-[3-(2-Chloro-phenyl)-ureido]-butylcarbamoyl}...)
Affinity DataIC50: 150nMAssay Description:Compound was evaluated for the binding affinity towards rat pancreatic Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Ccipe-Faculte De Pharmacie

Curated by ChEMBL
LigandPNGBDBM50089109([2-{4-[3-(2-Chloro-phenyl)-ureido]-butylcarbamoyl}...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type B receptor of mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
Ccipe-Faculte De Pharmacie

Curated by ChEMBL
LigandPNGBDBM50089109([2-{4-[3-(2-Chloro-phenyl)-ureido]-butylcarbamoyl}...)
Affinity DataIC50: 75nMAssay Description:Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article