BDBM50089189 4-Bromo-N-(1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-benzenesulfonamide::CHEMBL75183

SMILES CC1(C)[C@H]2CCC(C)(C2)[C@H]1NS(=O)(=O)c1ccc(Br)cc1

InChI Key InChIKey=SYWYQEXZLWDQAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089189   

TargetAmyloid-beta precursor protein(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50089189(4-Bromo-N-(1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of A-beta-42 production by inhibiting Gamma-secretase proteolytic pathway in HEK293 cell stably transfected with a double mutant form of h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed