BDBM50089190 CHEMBL450926::Thiophene-2-sulfonic acid (1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide

SMILES CC12CC[C@@H](C1)C(C)(C)[C@@H]2NS(=O)(=O)c1cccs1

InChI Key InChIKey=HASOGSNYTRWIAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089190   

TargetAmyloid-beta precursor protein(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50089190(Thiophene-2-sulfonic acid (1,3,3-trimethyl-bicyclo...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of A-beta-42 production by inhibiting Gamma-secretase proteolytic pathway in HEK293 cell stably transfected with a double mutant form of h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed