BDBM50089248 CHEMBL3577881

SMILES C[C@@H](N(Cc1cccc(c1)C(O)=O)C(=O)c1cc2ccccn2n1)c1ccc(F)cc1

InChI Key InChIKey=JIPVIQLALIVIQU-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089248   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50089248(CHEMBL3577881)Copy SMILESCopy InChI

Affinity DataIC50: 94nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/8/2016
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50089248(CHEMBL3577881)Copy SMILESCopy InChI

Affinity DataKi: >9.18E+3nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/8/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL