BDBM50089720 CHEMBL281677::[4-Benzo[1,3]dioxol-5-ylmethyl-2-(3-methoxy-benzyl)-5-trifluoromethyl-2H-pyrazol-3-yloxy]-acetic acid

SMILES COc1cccc(Cn2nc(c(Cc3ccc4OCOc4c3)c2OCC(O)=O)C(F)(F)F)c1

InChI Key InChIKey=NDGZHGVUBFMTQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089720   

TargetEndothelin-1 receptor(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089720([4-Benzo[1,3]dioxol-5-ylmethyl-2-(3-methoxy-benzyl...)
Affinity DataIC50: 450nMAssay Description:In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089720([4-Benzo[1,3]dioxol-5-ylmethyl-2-(3-methoxy-benzyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibition of [125-I] labelled ET-1 endothelin binding to Endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed