BDBM50089728 4-(4-Fluoro-benzyl)-2-(3-methoxy-benzyl)-5-trifluoromethyl-2H-pyrazol-3-ol::CHEMBL3144603

SMILES COc1cccc(Cn2[nH]c(c(Cc3ccc(F)cc3)c2=O)C(F)(F)F)c1

InChI Key InChIKey=LDCZCAXSPQFXDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089728   

TargetEndothelin-1 receptor(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089728(4-(4-Fluoro-benzyl)-2-(3-methoxy-benzyl)-5-trifluo...)
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed