BDBM50089736 4-Benzo[1,3]dioxol-5-ylmethyl-5-heptafluoropropyl-2-(3-methoxy-benzyl)-2H-pyrazol-3-ol::CHEMBL3144607

SMILES COc1cccc(Cn2[nH]c(c(Cc3ccc4OCOc4c3)c2=O)C(F)(F)C(F)(F)C(F)(F)F)c1

InChI Key InChIKey=IFPKLGTZNNODAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089736   

TargetEndothelin-1 receptor(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089736(4-Benzo[1,3]dioxol-5-ylmethyl-5-heptafluoropropyl-...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089736(4-Benzo[1,3]dioxol-5-ylmethyl-5-heptafluoropropyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [125-I] labelled ET-1 endothelin binding to Endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed