BDBM50090168 4-[2-((R)-4,4-Dimethyl-pentyl)-oxazol-5-yl]-N-{4-[2-(2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide::CHEMBL39804

SMILES CC(C)(C)CCCc1ncc(o1)-c1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1

InChI Key InChIKey=YLXXVTQNENXHGV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090168   

TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090168(4-[2-((R)-4,4-Dimethyl-pentyl)-oxazol-5-yl]-N-{4-[...)
Affinity DataEC50:  230nMAssay Description:In vitro efficacy at beta-3 adrenoceptors, quantified by measuring intracellular cAMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090168(4-[2-((R)-4,4-Dimethyl-pentyl)-oxazol-5-yl]-N-{4-[...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity at beta-2 adrenergic receptors in the presence of [125I]iodocyanopindolol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090168(4-[2-((R)-4,4-Dimethyl-pentyl)-oxazol-5-yl]-N-{4-[...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro binding affinity at beta-1 adrenergic receptors in the presence of [125I]iodocyanopindolol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed