BDBM50090170 CHEMBL285520::N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[2-((R)-4-trifluoromethyl-benzyl)-oxazol-4-yl]-benzenesulfonamide

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2coc(Cc3ccc(cc3)C(F)(F)F)n2)cc1)c1cccnc1

InChI Key InChIKey=XXQQFGMMETXGOJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090170   

TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090170(N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethy...)
Affinity DataEC50:  4.30nMAssay Description:In vitro efficacy at beta-3 adrenoceptors, quantified by measuring intracellular cAMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090170(N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethy...)
Affinity DataIC50: 310nMAssay Description:In vitro binding affinity at beta-2 adrenergic receptors in the presence of [125I]iodocyanopindolol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090170(N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethy...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro binding affinity at beta-1 adrenergic receptors in the presence of [125I]iodocyanopindolol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed