BDBM50090463 CHEMBL3581633

SMILES CC\C(=C(/c1ccccc1)c1ccc(\C=C\C(O)=O)cc1)c1ccc(O)cc1

InChI Key InChIKey=ZOHYRKHVFIHGOF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090463   

TargetEstrogen receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50090463(CHEMBL3581633)
Affinity DataIC50: 14nMAssay Description:Displacement of fluormone-labeled ES2 from recombinant full length human ERalpha ligand binding domain expressed in insect cells after 2 hrs by TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50090463(CHEMBL3581633)
Affinity DataEC50:  113nMAssay Description:Induction of estrogen receptor-alpha degradation in human MCF7 cells after 4 hrs by in-cell western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50090463(CHEMBL3581633)
Affinity DataIC50: 220nMAssay Description:Downregulation of ERalpha in human MCF7 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed