BDBM50090471 CHEMBL3581641

SMILES CC\C(=C(\c1ccc(\C=C\C(O)=O)cc1)c1ccc2[nH]ncc2c1)c1ccccc1

InChI Key InChIKey=PAAUSJRJCJHNJT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090471   

TargetEstrogen receptor(Human)
Seragon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090471(CHEMBL3581641)
Affinity DataEC50:  2.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal-stripped FBS incubated for 4 hrs by IRDye ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Seragon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090471(CHEMBL3581641)
Affinity DataEC50:  3nMAssay Description:Induction of estrogen receptor-alpha degradation in human MCF7 cells after 4 hrs by in-cell western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed