BDBM50090491 (R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-6-one O-benzyl-oxime::CHEMBL46773

SMILES Clc1ccc(cc1)[C@@H]1CCN2CC1\C(C2)=N\OCc1ccccc1

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090491   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090491((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  117nMAssay Description:Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090491((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090491((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090491((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  1.86E+3nMAssay Description:Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed