BDBM50090496 (R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-6-one O-tert-butyl-oxime::CHEMBL295880

SMILES CC(C)(C)O\N=C1/CN2CC1[C@@H](CC2)c1ccc(Cl)cc1

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090496   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090496((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  137nMAssay Description:Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090496((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  287nMAssay Description:Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090496((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  641nMAssay Description:Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090496((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  725nMAssay Description:Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed