BDBM50090639 (2Z,6E)-7,11-dimethyl-3-(propan-2-yl)dodeca-2,6,10-trien-1-yl (phosphonatooxy)phosphonate::3-substituted farnesyl diphosphate analogue

SMILES [#6]-[#6](-[#6])-[#6](\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]/[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O

InChI Key InChIKey=GXOMPOACQOQORK-UHFFFAOYSA-K

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090639   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Wayne State University

Curated by ChEMBL

LigandBDBM50090639((2Z,6E)-7,11-dimethyl-3-(propan-2-yl)dodeca-2,6,10...)Copy SMILESCopy InChI

Affinity DataIC50: 35nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
10/1/2012
Entry Details Article
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