BDBM50090686 2-Methyl-7-phenyl-[1,8]naphthyridine::2-methyl-7-phenyl-1,8-naphthyridine::7-Methyl-2-phenyl-1,8-naphthyridine::CHEMBL97344

SMILES Cc1ccc2ccc(nc2n1)-c1ccccc1

InChI Key InChIKey=BGLSJWRWFABGNC-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50090686   

TargetMetabotropic glutamate receptor 5(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090686(2-methyl-7-phenyl-1,8-naphthyridine | 2-Methyl-7-p...)
Affinity DataIC50: 664nMAssay Description:Antagonist activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Università

Curated by ChEMBL
LigandPNGBDBM50090686(2-methyl-7-phenyl-1,8-naphthyridine | 2-Methyl-7-p...)
Affinity DataKi:  6.90E+3nMAssay Description:Binding affinity against adenosine A1 receptor in bovine cortical membranes using [3H]CHA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Università

Curated by ChEMBL
LigandPNGBDBM50090686(2-methyl-7-phenyl-1,8-naphthyridine | 2-Methyl-7-p...)
Affinity DataKi:  6.90E+3nMAssay Description:Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50090686(2-methyl-7-phenyl-1,8-naphthyridine | 2-Methyl-7-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against adenosine A2 receptor in bovine striatal membranes using [3H]-CGS-21,680 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50090686(2-methyl-7-phenyl-1,8-naphthyridine | 2-Methyl-7-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against adenosine A1 receptor in human cortical membranes using [3H]CHA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50090686(2-methyl-7-phenyl-1,8-naphthyridine | 2-Methyl-7-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against adenosine A2 receptor in human striatal membranes using [3H]CGS-21680 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50090686(2-methyl-7-phenyl-1,8-naphthyridine | 2-Methyl-7-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from rat testis membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50090686(2-methyl-7-phenyl-1,8-naphthyridine | 2-Methyl-7-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace the specific binding of [3H]-CGS- to adenosine A2A receptor form bovine brain striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed