BDBM50090764 (R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxylic acid amide::CHEMBL97268

SMILES CCCN(C(C)C)C1COc2cccc(C(N)=O)c2C1

InChI Key InChIKey=HSIWCIOUGIRMGE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090764   

Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi:  0.480nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at D1 receptor by measuring its ability to displace [3H]SCH-23390 from Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi: >5.00E+4nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2A measured by ability to displace [3H]raclopride from D2A receptor expressed in mouse f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed